Opportunity Information: Apply for PAR 18 733
The National Institutes of Health (NIH), through the NIH Common Fund, offered this funding opportunity to support small, focused research projects that use or help expand the Gabriella Miller Kids First (Kids First) Data Resource. Kids First is a pediatric research program built around a shared data resource that combines genome sequencing data with detailed phenotype (clinical and trait) information. The core purpose is to give researchers who study the genetics of childhood cancers and structural birth defects a high-value, broadly accessible dataset that can speed up discovery about disease mechanisms. Over time, those discoveries are expected to contribute to better diagnostics and, ultimately, more targeted treatments for affected children.
This particular announcement uses the NIH R03 mechanism, which is designed for smaller, limited-scope projects. In practical terms, it is meant for discrete analyses, pilot-style studies, or narrowly defined methods work that can be completed with modest resources. The emphasis is on meritorious projects that either analyze existing Kids First datasets (or datasets that could be incorporated into Kids First) or that improve the way researchers can analyze genome-wide data in these disease areas. In addition to direct data analyses, applicants may propose development of statistical or computational methodology tailored to genome-scale datasets relevant to pediatric cancer and/or structural birth defects, as long as the work aligns with the Kids First mission and supports better use of shared pediatric genomic-phenotypic data.
The broader Kids First program goal is twofold: first, to obtain and aggregate genome sequence and phenotype data from as many relevant cohorts as possible across childhood cancers and structural birth defects, and second, to advance research by enabling broad data sharing with the research community. This funding opportunity fits into that strategy by encouraging investigators to do high-impact analyses on these shared datasets and to develop analytic approaches that make the resource more scientifically productive for many users, not just a single lab. The title also specifies "Clinical Trial Not Allowed," meaning the proposed research cannot include a clinical trial component under NIH definitions, and the work should remain within the bounds of data-focused research and methods development rather than interventional studies.
Key administrative details included an award ceiling of $200,000 and a closing date listed as November 16, 2018, under Funding Opportunity Number PAR-18-733. The opportunity category is discretionary, the instrument type is a grant, and the activity category is associated with health-related research. Multiple CFDA numbers are referenced (including 93.121, 93.233, 93.273, 93.837, 93.838, 93.839, 93.865, and 93.940), reflecting the NIH institutes and programs connected to the initiative.
Eligibility was broad and included many types of domestic organizations and governments: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly highlighted additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities (foreign organizations). In short, NIH structured eligibility to encourage wide participation, including institutions and communities that are often underrepresented in large-scale genomics research.
Overall, the opportunity was meant to catalyze smaller, high-value projects that leverage the Kids First Data Resource to uncover genetic contributors to pediatric cancers and structural birth defects, improve genome-wide analytic methods in these areas, and strengthen an integrated, shared pediatric data ecosystem that can be reused broadly by the research community.Apply for PAR 18 733
- The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "Small Research Grants for Analyses of Data for the Gabriella Miller Kids First Data Resource (R03 - Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.233, 93.273, 93.837, 93.838, 93.839, 93.865, 93.940.
- This funding opportunity was created on 2018-03-30.
- Applicants must submit their applications by 2018-11-16. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| Identification and Management of Behavioral Symptoms and Mental Health Conditions in Individuals with Intellectual Disabilities (R01 - Clinical Trial Optional) Apply for PAR 18 766 Funding Number: PAR 18 766 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Patient Safety in the Context of Perinatal, Neonatal, and Pediatric Care (R01 - Clinical Trial Optional) Apply for PA 18 790 Funding Number: PA 18 790 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Patient Safety in the Context of Perinatal, Neonatal, and Pediatric Care (R03 - Clinical Trial Optional) Apply for PA 18 791 Funding Number: PA 18 791 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Rare Genetic Syndromes as a Window into the Genetic Architecture of Mental Disorders (Collaborative U01 Clinical Trial Not Allowed) Apply for RFA MH 19 201 Funding Number: RFA MH 19 201 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Rare Genetic Syndromes as a Window into the Genetic Architecture of Mental Disorders (U01 Clinical Trial Not Allowed) Apply for RFA MH 19 200 Funding Number: RFA MH 19 200 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Immune Mechanisms at the Maternal-Fetal Interface (R01 Clinical Trial Optional) Apply for RFA AI 18 023 Funding Number: RFA AI 18 023 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| The Role of Epitranscriptomics in Development and Disease (R21 - Clinical Trial Not Allowed) Apply for PAR 18 831 Funding Number: PAR 18 831 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Development of Novel Nonsteroidal Contraceptive Methods (R61/R33 - Clinical Trial Not Allowed) Apply for RFA HD 19 015 Funding Number: RFA HD 19 015 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $500,000 |
| Enhancing Developmental Biology Research at Academic Research Enhancement Award Eligible Institutions (R15 - Clinical Trial Not Allowed) Apply for PAR 18 834 Funding Number: PAR 18 834 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $300,000 |
| Role of Gut Microbiome in Regulating Reproduction and Its Impact on Fertility Status in Women Living with and Without HIV (R01 - Clinical Trial Optional) Apply for PA 18 838 Funding Number: PA 18 838 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $499,999 |
| Role of Gut Microbiome in Regulating Reproduction and Its Impact on Fertility Status in Women Living with and Without HIV (R21 Clinical Trial Optional) Apply for PA 18 839 Funding Number: PA 18 839 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Pediatric Critical Care and Trauma Scientist Development Program (K12 Clinical Trial Optional) Apply for RFA HD 19 008 Funding Number: RFA HD 19 008 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $600,000 |
| Novel Approaches to Safe, Non-Invasive, Real Time Assessment of Human Placenta Development and Function Across Pregnancy (R21 - Clinical Trial Not Allowed) Apply for PAR 18 885 Funding Number: PAR 18 885 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Novel Approaches to Safe, Non-Invasive, Real Time Assessment of Human Placenta Development and Function Across Pregnancy (R01 - Clinical Trial Not Allowed) Apply for PAR 18 884 Funding Number: PAR 18 884 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed) Apply for PAR 18 953 Funding Number: PAR 18 953 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Trial Not Allowed) Apply for PAR 18 952 Funding Number: PAR 18 952 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Reproductive Medicine Collaborative Clinical Trials Program (Collaborative R01 Clinical Trial Required) Apply for RFA HD 19 022 Funding Number: RFA HD 19 022 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Antenatal Opioid Exposure Longitudinal Study Consortium (PL1 Clinical Trials Not Allowed) Apply for RFA HD 19 025 Funding Number: RFA HD 19 025 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Contraception Research Centers Program (U54 Clinical Trial Optional) Apply for RFA HD 19 023 Funding Number: RFA HD 19 023 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Womens HIV Epidemiology Cohort Studies (R01 Clinical Trial Not Allowed) Apply for RFA HD 19 024 Funding Number: RFA HD 19 024 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $250,000 |
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