Opportunity Information: Apply for RFA CE 16 001

The Research Grants for Preventing Violence and Violence Related Injury (R01) opportunity (Funding Opportunity Number RFA CE 16 001) is a CDC National Center for Injury Prevention and Control (NCIPC) research initiative focused on strengthening the evidence base for primary prevention of violence and violence-related injury. The core aim is to support investigator-initiated studies that either (1) improve understanding of how to disseminate, implement, and translate evidence-based prevention strategies in real-world settings, or (2) rigorously evaluate prevention strategies, programs, or policies to determine what works, for whom, and under what conditions. The emphasis is on filling practical gaps that keep proven or promising approaches from being adopted effectively at scale and on producing strong evaluation evidence that can guide public health and community decision-making.

Programmatically, the grant targets four major violence domains: child abuse and neglect, teen dating violence, intimate partner violence, and sexual violence. Projects are expected to focus on primary prevention, meaning they are oriented toward stopping violence before it starts rather than responding after violence has occurred. The initiative specifically calls for strategies, programs, or policies that serve either universal populations (broad groups regardless of risk level) or selected high-risk populations, defined here as groups with one or more risk factors that increase the likelihood of initial perpetration of violence. In practice, this framing supports research that tests prevention approaches upstream, including community, school, healthcare, and policy environments, and that pays attention to implementation realities such as reach, fidelity, adaptation, sustainability, and scalability.

A distinguishing feature of the opportunity is its dual interest in both effectiveness and implementation. On one side, NCIPC is looking for rigorous evaluations that can credibly answer whether a prevention approach reduces violence or related injuries and closes known evidence gaps in the listed violence areas. On the other side, it is also looking for dissemination and implementation research that examines how evidence-based interventions can be translated into routine practice, what barriers and facilitators matter most, and what strategies improve uptake across different systems and settings. This makes the opportunity relevant to investigators working in public health, behavioral science, social services, education, criminal justice-adjacent prevention systems, and community-based prevention infrastructures, especially when research designs are strong and outcomes are clearly tied to violence prevention.

The funding mechanism is a cooperative agreement, meaning CDC is expected to have substantial involvement during the project period compared with a standard grant. While the solicitation text provided does not spell out the exact nature of that involvement, cooperative agreements typically include collaboration with CDC on technical guidance, alignment with program priorities, and monitoring of progress toward shared outcomes. The award ceiling is $350,000, and the CDC anticipated making about 3 awards under this opportunity. The CFDA number listed is 93.136. The original closing date for applications was March 1, 2016, indicating this specific announcement is historical, though it reflects CDC priorities and structures commonly seen in violence prevention research funding.

Eligibility is broad and includes many types of organizations that can conduct or support research, such as state, county, city/township, special district governments, independent school districts, public and private institutions of higher education, federally recognized tribal governments, tribal organizations, public housing authorities/Indian housing authorities, nonprofits with and without 501(c)(3) status (other than institutions of higher education), for-profit organizations (other than small businesses), and small businesses. The announcement also highlights that certain higher education institutions are encouraged to apply, including Hispanic-serving institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, and Alaska Native and Native Hawaiian Serving Institutions. Additional eligible categories include eligible federal agencies, U.S. territories or possessions, faith-based and community-based organizations, regional organizations, bona fide agents applying on behalf of a state or local government (with required legal documentation attached in the application), and Federally Funded Research and Development Centers (FFRDCs).

Overall, this opportunity is designed to move the field beyond knowing that prevention can work toward knowing how to make it work consistently across communities. It prioritizes research that produces actionable findings: evidence that supports decisions about adopting, adapting, and scaling prevention strategies that reduce child abuse and neglect, teen dating violence, intimate partner violence, and sexual violence, with attention to both measurable outcomes and the practical steps needed to implement prevention effectively in real-world systems.

  • The Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Research Grants for Preventing Violence and Violence Related Injury (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136.
  • This funding opportunity was created on 2015-11-30.
  • Applicants must submit their applications by 2016-03-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $350,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others.
Apply for RFA CE 16 001

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FAQs: Research Grants for Preventing Violence and Violence Related Injury (R01) (RFA-CE-16-001)

What is this funding opportunity?

This opportunity is the CDC National Center for Injury Prevention and Control (NCIPC) initiative titled "Research Grants for Preventing Violence and Violence Related Injury (R01)," Funding Opportunity Number RFA-CE-16-001. It supports research to strengthen the evidence base for the primary prevention of violence and violence-related injury.

What is the main goal of the program?

The core goal is to fund investigator-initiated studies that generate actionable evidence for preventing violence before it starts. The program is designed to help move the field from knowing that prevention can work to knowing how to make prevention work consistently in real-world settings and at scale.

What types of studies does the program support?

The opportunity emphasizes two broad study types:

  • Dissemination, implementation, and translation research that improves understanding of how to adopt and use evidence-based prevention strategies in real-world settings (including barriers, facilitators, and implementation strategies).
  • Rigorous evaluations of prevention strategies, programs, or policies to determine what works, for whom, and under what conditions.

What does "primary prevention" mean in this announcement?

Primary prevention means focusing on stopping violence before it occurs, rather than responding after violence has already happened. Projects are expected to be oriented upstream, with a prevention focus rather than an intervention or response focus after violence occurs.

Which violence domains are included?

The grant targets four major violence domains:

  • Child abuse and neglect
  • Teen dating violence
  • Intimate partner violence
  • Sexual violence

Is the program focused more on effectiveness research or implementation research?

It is explicitly interested in both. NCIPC is looking for strong evidence on whether approaches reduce violence or related injuries (effectiveness) and also for research that explains how evidence-based strategies can be disseminated and implemented successfully in routine practice (implementation).

What does the announcement mean by "real-world settings"?

Based on the description provided, "real-world settings" include environments where prevention strategies may be adopted and delivered in practice, such as community contexts, schools, healthcare-related environments, and policy settings, with attention to practical implementation realities.

What kinds of populations should projects serve?

The opportunity calls for strategies, programs, or policies that serve either:

  • Universal populations (broad groups regardless of risk level), or
  • Selected high-risk populations, defined here as groups with one or more risk factors that increase the likelihood of initial perpetration of violence.

What implementation issues are expected to be addressed?

The opportunity highlights implementation realities such as reach, fidelity, adaptation, sustainability, and scalability. Projects aligned with the announcement would be expected to pay attention to these kinds of factors when studying how prevention approaches are used in practice.

What kinds of outcomes does CDC want from funded research?

The program emphasizes producing strong, actionable evidence to guide public health and community decision-making. This includes credible findings on whether a prevention approach reduces violence or related injuries and practical evidence on how to implement and scale prevention strategies effectively.

What is the funding mechanism?

The funding mechanism is a cooperative agreement. This indicates CDC is expected to have substantial involvement during the project period compared with a standard grant.

How involved is CDC during the project?

The text provided states that CDC is expected to have substantial involvement, though it does not specify exact activities. It notes that cooperative agreements typically involve collaboration with CDC on technical guidance, alignment with program priorities, and monitoring progress toward shared outcomes.

What is the maximum award amount (award ceiling)?

The award ceiling listed is $350,000.

How many awards were expected?

CDC anticipated making about 3 awards under this opportunity.

What is the CFDA number for this opportunity?

The CFDA number listed is 93.136.

Is this opportunity still open?

The original closing date for applications was March 1, 2016. Based on that date, this specific announcement is historical rather than currently open.

Who is eligible to apply?

Eligibility is described as broad and includes many organization types, including:

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and private institutions of higher education
  • Federally recognized tribal governments
  • Tribal organizations
  • Public housing authorities / Indian housing authorities
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • For-profit organizations (other than small businesses)
  • Small businesses
  • Eligible federal agencies
  • U.S. territories or possessions
  • Faith-based organizations
  • Community-based organizations
  • Regional organizations
  • Federally Funded Research and Development Centers (FFRDCs)

Are any specific types of colleges and universities encouraged to apply?

Yes. The announcement notes that certain higher education institutions are encouraged to apply, including:

  • Hispanic-serving institutions
  • Historically Black Colleges and Universities (HBCUs)
  • Tribally Controlled Colleges and Universities
  • Alaska Native and Native Hawaiian Serving Institutions

Can an agent apply on behalf of a state or local government?

Yes. The opportunity includes "bona fide agents" applying on behalf of a state or local government, with the note that required legal documentation must be attached in the application.

What disciplines or sectors are most relevant for applicants?

The description suggests this opportunity is relevant to investigators working in public health, behavioral science, social services, education, criminal justice-adjacent prevention systems, and community-based prevention infrastructures, especially where study designs are strong and outcomes are clearly tied to violence prevention.

What kind of evidence gaps is the program trying to fill?

The opportunity emphasizes filling practical gaps that keep proven or promising approaches from being adopted effectively at scale, and generating rigorous evaluation evidence to clarify what works, for whom, and under what conditions across the listed violence domains.

What is the overall intent of the initiative?

The overall intent is to strengthen both the effectiveness evidence and the implementation evidence for violence prevention, producing findings that can support decisions about adopting, adapting, and scaling strategies that reduce child abuse and neglect, teen dating violence, intimate partner violence, and sexual violence.

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