Opportunity Information: Apply for PA 19 086
The Mentored Clinical Scientist Research Career Development Award (K08) under PA-19-086 is an NIH career development grant meant to help clinically trained researchers become independent investigators whose work addresses important U.S. health research needs. The core idea is to give early-career professionals with a clinical doctoral degree sustained, protected time to build deep research expertise under the guidance of experienced mentors. It supports an intensive, supervised career development period in biomedical and behavioral research, including translational research, with the expectation that recipients will come out of the award positioned to compete successfully for independent research funding and to lead impactful research programs.
What makes this specific K08 announcement distinct is that it is tailored to applicants who will lead independent basic experimental studies involving humans. NIH treats these projects as clinical trials because they prospectively involve human participants and assign them to conditions, but they are also considered basic research because the intent is to understand fundamental mechanisms or phenomena rather than to test a product or directly develop an applied intervention. In practical terms, the projects targeted here are ones where the investigator experimentally manipulates an independent variable in people and measures biomedical or behavioral outcomes to answer basic science questions, without a primary goal of creating or optimizing a process, treatment, device, or other product. If the proposed human study is experimental but is aimed at a specific practical application or product-focused development pathway, NIH indicates that it should be submitted to the companion opportunity (PA-18-372) rather than to this FOA.
The funding instrument is a grant, and the opportunity sits within broad public-purpose categories that include education, environment, health, and social services. It is administered by the National Institutes of Health and is associated with multiple CFDA numbers (93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.307, 93.853, 93.865, 93.866, 93.867), reflecting that different NIH institutes and centers participate and may support K08 awards aligned with their missions.
Eligibility is wide on the applicant organization side. Eligible applicants include many types of U.S. organizations and governmental entities, such as public and private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) organizations), for-profit organizations (other than small businesses), small businesses, and a variety of government bodies (state, county, city/township, special district governments, independent school districts, and certain housing authorities). Tribal entities are included as well, both federally recognized Native American tribal governments and tribal organizations that are not federally recognized. The announcement also highlights additional eligible applicant categories often emphasized for NIH participation, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), along with faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
At the same time, NIH draws clear lines around foreign involvement at the applicant level. Non-domestic (non-U.S.) entities and non-U.S. institutions are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are also not eligible. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed, meaning the research program may include certain foreign collaborations or elements when justified and compliant with NIH policy, even though the primary applicant organization must be domestic.
Key administrative details in the source information include the funding opportunity title and number (Mentored Clinical Scientist Research Career Development Award (Parent K08 - Independent Basic Experimental Studies with Humans Required), PA-19-086), the original closing date listed as 2020-05-12, and the creation date of 2018-11-28. The award ceiling and expected number of awards are not specified in the provided data, which is common in NIH FOAs where budgets and award counts can vary by institute, fiscal year, and program priorities.Apply for PA 19 086
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Mentored Clinical Scientist Research Career Development Award (Parent K08 - Independent Basic Experimental Studies with Humans Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.307, 93.853, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2018-11-28.
- Applicants must submit their applications by 2020-05-12. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) (Collaborative R34- Clinical Trial Not Allowed) Apply for RFA DA 19 029 Funding Number: RFA DA 19 029 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $225,000 |
| Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Apply for PAR 19 134 Funding Number: PAR 19 134 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $300,000 |
| HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) ( R34- Clinical Trial Not Allowed) Apply for RFA DA 19 036 Funding Number: RFA DA 19 036 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $225,000 |
| Limited Competition for a Connectome Coordination Facility (R24 Clinical Trial Not Allowed) Apply for RFA MH 20 210 Funding Number: RFA MH 20 210 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $900,000 |
| Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) Apply for RFA OD 19 016 Funding Number: RFA OD 19 016 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Clinical Trials Development for Co-Occurring Conditions in Individuals with Down syndrome: Phased Awards for INCLUDE (R61/R33 Clinical Trials Required) Apply for RFA OD 19 018 Funding Number: RFA OD 19 018 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed) Apply for RFA OD 19 015 Funding Number: RFA OD 19 015 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required Apply for PA 19 273 Funding Number: PA 19 273 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) Apply for PAR 19 276 Funding Number: PAR 19 276 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) Apply for PAR 19 274 Funding Number: PAR 19 274 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Marmoset Coordination Center (U24 Clinical Trials Not Allowed) Apply for RFA MH 20 150 Funding Number: RFA MH 20 150 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Marmoset Colonies for Neuroscience Research (U24 Clinical Trials Not Allowed) Apply for RFA MH 20 145 Funding Number: RFA MH 20 145 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint for Neuroscience Research Education Program on Translational Devices (R25 Clinical Trial Not Allowed) Apply for RFA NS 20 003 Funding Number: RFA NS 20 003 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $250,000 |
| NIH Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP-ENDURE) (R25 Clinical Trial Not Allowed) Apply for RFA NS 20 015 Funding Number: RFA NS 20 015 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed) Apply for RFA OD 20 004 Funding Number: RFA OD 20 004 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) Apply for PA 20 142 Funding Number: PA 20 142 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) Apply for PA 20 184 Funding Number: PA 20 184 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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| Mentored Quantitative Research Development Award (Parent K25 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 198 Funding Number: PA 20 198 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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